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Simvastatin attenuates microglia, astrocyte activation and decreases IL-1β Level following traumatic brain injury

OBJECTIVE: Our previous studies demonstrated that simvastatin promotes neurological functional recovery after traumatic brain injury (TBI) in rat; however, the underlying mechanisms remain poorly understood. The purpose of this study was to investigate the anti-inflammatory effect of simvastatin by...

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Hlavní autoři: Li, Bo, Mahmood, Asim, Lu, Dunyue, Wu, Hongtao, Xiong, Ye, Qu, Changsheng, Chopp, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749520/
https://ncbi.nlm.nih.gov/pubmed/19574840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.NEU.0000346272.76537.DC
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