Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics

Early full-term pregnancy is one of the most effective natural protections against breast cancer. To investigate this effect, we have characterized the global gene expression and epigenetic profiles of multiple cell types from normal breast tissue of nulliparous and parous women, and carriers of BRC...

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Hoofdauteurs: Choudhury, Sibgat, Almendro, Vanessa, Merino, Vanessa F., Wu, Zhenhua, Maruyama, Reo, Su, Ying, Martins, Filipe C., Fackler, Mary Jo, Bessarabova, Marina, Kowalczyk, Adam, Conway, Thomas, Beresford-Smith, Bryan, Macintyre, Geoff, Cheng, Yu-Kang, Lopez-Bujanda, Zoila, Kaspi, Antony, Hu, Rong, Robens, Judith, Nikolskaya, Tatiana, Haakensen, Vilde D., Schnitt, Stuart J., Argani, Pedram, Ethington, Gabrielle, Panos, Laura, Grant, Michael, Clark, Jason, Herlihy, William, Lin, S. Joyce, Chew, Grace, Thompson, Erik W., Greene-Colozzi, April, Richardson, Andrea L., Rosson, Gedge D., Pike, Malcolm, Garber, Judy E., Nikolsky, Yuri, Blum, Joanne L., Au, Alfred, Hwang, E. Shelley, Tamimi, Rulla M., Michor, Franziska, Haviv, Izhak, Liu, X. Shirley, Sukumar, Saraswati, Polyak, Kornelia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703476/
https://ncbi.nlm.nih.gov/pubmed/23770079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.05.004
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