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Non-cell autonomous tumor-growth driving supports sub-clonal heterogeneity
Cancers arise through a process of somatic evolution that can result in substantial sub-clonal heterogeneity within tumors. The mechanisms responsible for the coexistence of distinct sub-clones and the biological consequences of this coexistence remain poorly understood. Here we used a mouse xenogra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4184961/ https://ncbi.nlm.nih.gov/pubmed/25079331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13556 |
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