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Differential network analysis for the identification of condition-specific pathway activity and regulation

Motivation: Identification of differential expressed genes has led to countless new discoveries. However, differentially expressed genes are only a proxy for finding dysregulated pathways. The problem is to identify how the network of regulatory and physical interactions rewires in different conditi...

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Detalhes bibliográficos
Main Authors: Gambardella, Gennaro, Moretti, Maria Nicoletta, de Cegli, Rossella, Cardone, Luca, Peron, Adriano, di Bernardo, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702259/
https://ncbi.nlm.nih.gov/pubmed/23749957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt290
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