GADD34 is a modulator of autophagy during starvation

Cells respond to starvation by shutting down protein synthesis and by activating catabolic processes, including autophagy, to recycle nutrients. This two-pronged response is mediated by the integrated stress response (ISR) through phosphorylation of eIF2α, which represses protein translation, and by...

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Vydáno v:Sci Adv
Hlavní autoři: Gambardella, Gennaro, Staiano, Leopoldo, Moretti, Maria Nicoletta, De Cegli, Rossella, Fagnocchi, Luca, Di Tullio, Giuseppe, Polletti, Sara, Braccia, Clarissa, Armirotti, Andrea, Zippo, Alessio, Ballabio, Andrea, De Matteis, Maria Antonietta, di Bernardo, Diego
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518873/
https://ncbi.nlm.nih.gov/pubmed/32978159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb0205
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