Primary Cervical Carcinoma Cell Lines Overexpress Epithelial Cell Adhesion Molecule (EpCAM) and Are Highly Sensitive to Immunotherapy With MT201, a Fully Human Monoclonal Anti-EpCAM Antibody

INTRODUCTION: Epithelial cell adhesion molecule (EpCAM) is a surface glycoprotein highly differentially expressed in many epithelial malignancies. The goal of this study was to evaluate the expression of EpCAM and the potential of MT201 (adecatumumab), a human monoclonal antibody targeting EpCAM, ag...

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Main Authors: Richter, Christine E., Cocco, Emiliano, Bellone, Stefania, Bellone, Marta, Casagrande, Francesca, Todeschini, Paola, Rüttinger, Dominik, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701951/
https://ncbi.nlm.nih.gov/pubmed/21370592
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