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Blocking HIV-1 gp120 at the Phe43 Cavity: If the Extension Fits
The Phe43 cavity is a mysterious feature in crystallographic structures of HIV-1 gp120-CD4 complexes. In this Structure issue, Acharya and colleagues provide structural explanations for the potent neutralization by CD4 mimetic miniproteins with chemical extensions that fit into this cavity.
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701939/ https://ncbi.nlm.nih.gov/pubmed/23747109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.05.004 |
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