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Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack
UV-induced DNA damage causes repression of RNA synthesis. Following the removal of DNA lesions, transcription recovery operates through a process that is not understood yet. Here we show that knocking-out of the histone methyltransferase DOT1L in mouse embryonic fibroblasts (MEF(DOT1L)) leads to a U...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701700/ https://ncbi.nlm.nih.gov/pubmed/23861670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003611 |
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