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The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle

Dot1/DOT1L catalyzes the methylation of histone H3 lysine 79 (H3K79), which regulates diverse cellular processes, such as development, reprogramming, differentiation, and proliferation. In regards to these processes, studies of Dot1/DOT1L-dependent H3K79 methylation have mainly focused on the transc...

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Detalhes bibliográficos
Main Authors: Kim, Wootae, Choi, Minji, Kim, Ja-Eun
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979909/
https://ncbi.nlm.nih.gov/pubmed/24526115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28104
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