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The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis
Osteoclasts are absorptive cells that play a critical role in homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role of epigenetic regulation in osteoclastogenesis. In this study, we investigated the role of DOT1L, which regulates gene expression e...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833786/ https://ncbi.nlm.nih.gov/pubmed/29348610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0040-5 |
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