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The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis
Osteoclasts are absorptive cells that play a critical role in homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role of epigenetic regulation in osteoclastogenesis. In this study, we investigated the role of DOT1L, which regulates gene expression e...
Gespeichert in:
| Veröffentlicht in: | Cell Death Dis |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833786/ https://ncbi.nlm.nih.gov/pubmed/29348610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0040-5 |
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