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Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers
Age-associated telomere shortening leads to replicative senescence of human endothelial cells (EC). Risk factors for cardiovascular disease (CVD) accelerate ageing, while there is a concomitant rise in oxidative stress known to promote stress-induced senescence (SIS) in vitro. Of all risk factors fo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701584/ https://ncbi.nlm.nih.gov/pubmed/19011671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/Y08-082 |
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