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Impaired α(IIb)β(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1
Platelet aggregation is essential for hemostasis, but can also cause myocardial infarction and stroke. A key but poorly understood step in platelet activation is increased function of the major adhesive receptor, α(IIb)β(3) integrin, which enables adhesion and aggregation. Phospholipases (PL), in re...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701458/ https://ncbi.nlm.nih.gov/pubmed/20051593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000551 |
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