Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis

Genetically modified mice are indispensable for establishing the roles of platelets in arterial thrombosis and hemostasis. Microfluidics assays using anticoagulated whole blood are commonly used as integrative proxy tests for platelet function in mice. In the present study, we quantified the changes...

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Publicado en:Front Cardiovasc Med
Main Authors: Nagy, Magdolna, van Geffen, Johanna P., Stegner, David, Adams, David J., Braun, Attila, de Witt, Susanne M., Elvers, Margitta, Geer, Mitchell J., Kuijpers, Marijke J. E., Kunzelmann, Karl, Mori, Jun, Oury, Cécile, Pircher, Joachim, Pleines, Irina, Poole, Alastair W., Senis, Yotis A., Verdoold, Remco, Weber, Christian, Nieswandt, Bernhard, Heemskerk, Johan W. M., Baaten, Constance C. F. M. J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Cardiovascular Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682619/
https://ncbi.nlm.nih.gov/pubmed/31417909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00099
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