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Facilitating roles of murine platelet glycoprotein Ib and αIIbβ3 in phosphatidylserine exposure during vWF–collagen-induced thrombus formation
Vessel wall damage exposes collagen fibres, to which platelets adhere directly via the collagen receptors glycoprotein (GP) VI and integrin α(2)β(1) and indirectly by collagen-bound von Willebrand factor (vWF) via the GPIb-V-IX and integrin αIIbβ3 receptor complexes. Platelet–collagen interaction un...
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Autores principales: | , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Blackwell Science Inc
2004
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664961/ https://ncbi.nlm.nih.gov/pubmed/15155790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.062414 |
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