Facilitating roles of murine platelet glycoprotein Ib and αIIbβ3 in phosphatidylserine exposure during vWF–collagen-induced thrombus formation

Vessel wall damage exposes collagen fibres, to which platelets adhere directly via the collagen receptors glycoprotein (GP) VI and integrin α(2)β(1) and indirectly by collagen-bound von Willebrand factor (vWF) via the GPIb-V-IX and integrin αIIbβ3 receptor complexes. Platelet–collagen interaction un...

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Autors principals: Kuijpers, Marijke J E, Schulte, Valerie, Oury, Cécile, Lindhout, Theo, Broers, Jos, Hoylaerts, Marc F, Nieswandt, Bernhard, Heemskerk, Johan W M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664961/
https://ncbi.nlm.nih.gov/pubmed/15155790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.062414
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