Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

The expansion of repressive epigenetic marks has been implicated in heterochromatin formation during embryonic development, but the general applicability of this mechanism is unclear. Here we show that nuclear rearrangement of repressive histone marks H3K9me3 and H3K27me3 into nonoverlapping structu...

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Main Authors: Chandra, Tamir, Kirschner, Kristina, Thuret, Jean-Yves, Pope, Benjamin D., Ryba, Tyrone, Newman, Scott, Ahmed, Kashif, Samarajiwa, Shamith A., Salama, Rafik, Carroll, Thomas, Stark, Rory, Janky, Rekin’s, Narita, Masako, Xue, Lixiang, Chicas, Agustin, Nũnez, Sabrina, Janknecht, Ralf, Hayashi-Takanaka, Yoko, Wilson, Michael D., Marshall, Aileen, Odom, Duncan T., Babu, M. Madan, Bazett-Jones, David P., Tavaré, Simon, Edwards, Paul A.W., Lowe, Scott W., Kimura, Hiroshi, Gilbert, David M., Narita, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701408/
https://ncbi.nlm.nih.gov/pubmed/22795131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.010
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