Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia

STUDY OBJECTIVE: To evaluate the pharmacokinetics of gentamicin in neonates with hypoxic ischemic encephalopathy (HIE) receiving hypothermia and to identify an empiric gentamicin dosing strategy in this population that optimizes achievement of target peak and trough concentrations. DESIGN: Populatio...

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Main Authors: Frymoyer, Adam, Meng, Lina, Bonifacio, Sonia L., Verotta, Davide, Guglielmo, B. Joseph
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700641/
https://ncbi.nlm.nih.gov/pubmed/23553582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1263
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