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Decreased Morphine Clearance in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia

Morphine is commonly used in neonates with hypothermic ischemic encephalopathy (HIE) during therapeutic hypothermia to provide comfort and analgesia. However, pharmacokinetic data to support morphine dosing in this vulnerable population are lacking. A prospective, two-center, clinical pharmacokineti...

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Detalles Bibliográficos
Publicado en:J Clin Pharmacol
Main Authors: Frymoyer, Adam, Bonifacio, Sonia L., Drover, David R., Su, Felice, Wustoff, Courtney J, Van Meurs, Krisa P.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240044/
https://ncbi.nlm.nih.gov/pubmed/27225747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.775
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