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Decreased Morphine Clearance in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia

Morphine is commonly used in neonates with hypothermic ischemic encephalopathy (HIE) during therapeutic hypothermia to provide comfort and analgesia. However, pharmacokinetic data to support morphine dosing in this vulnerable population are lacking. A prospective, two-center, clinical pharmacokineti...

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Bibliografiska uppgifter
I publikationen:J Clin Pharmacol
Huvudupphovsmän: Frymoyer, Adam, Bonifacio, Sonia L., Drover, David R., Su, Felice, Wustoff, Courtney J, Van Meurs, Krisa P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240044/
https://ncbi.nlm.nih.gov/pubmed/27225747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.775
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