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Decreased Morphine Clearance in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia

Morphine is commonly used in neonates with hypothermic ischemic encephalopathy (HIE) during therapeutic hypothermia to provide comfort and analgesia. However, pharmacokinetic data to support morphine dosing in this vulnerable population are lacking. A prospective, two-center, clinical pharmacokineti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Pharmacol
Prif Awduron: Frymoyer, Adam, Bonifacio, Sonia L., Drover, David R., Su, Felice, Wustoff, Courtney J, Van Meurs, Krisa P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240044/
https://ncbi.nlm.nih.gov/pubmed/27225747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.775
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