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A modified Sleeping Beauty transposon system that can be used to model a wide variety of human cancers in mice

Recent advances in cancer therapeutics stress the need for a better understanding of the molecular mechanisms driving tumor formation. This can be accomplished by obtaining a more complete description of the genes that contribute to cancer. We previously described an approach using the Sleeping Beau...

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Main Authors: Dupuy, Adam J., Rogers, Laura M., Kim, Jinsil, Nannapaneni, Kishore, Starr, Timothy K., Liu, Pentao, Largaespada, David A., Scheetz, Todd E., Jenkins, Nancy A., Copeland, Neal G.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700628/
https://ncbi.nlm.nih.gov/pubmed/19808965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1135
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