Adoptive Transfer of Lymphocytes Isolated from Simian Immunodeficiency Virus SIVmac239Δnef-Vaccinated Macaques Does Not Affect Acute-Phase Viral Loads but May Reduce Chronic-Phase Viral Loads in Major Histocompatibility Complex-Matched Recipients

The live attenuated simian immunodeficiency virus (SIV) SIVmac239Δnef is the most effective SIV/human immunodeficiency virus (HIV) vaccine in preclinical testing. An understanding of the mechanisms responsible for protection may provide important insights for the development of HIV vaccines. Leverag...

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Autors principals: Greene, Justin M., Lhost, Jennifer J., Hines, Paul J., Scarlotta, Matthew, Harris, Max, Burwitz, Benjamin J., Budde, Melisa L., Dudley, Dawn M., Pham, Ngoc, Cain, Brian, Mac Nair, Caitlin E., Weiker, Madelyn K., O'Connor, Shelby L., Friedrich, Thomas C., O'Connor, David H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700297/
https://ncbi.nlm.nih.gov/pubmed/23616658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00348-13
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