Hepatitis C Virus Infection Upregulates CD55 Expression on the Hepatocyte Surface and Promotes Association with Virus Particles

CD55 limits excessive complement activation on the host cell surface by accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes upregulated CD55 expression at the mRNA and pro...

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Autori principali: Mazumdar, Budhaditya, Kim, Hangeun, Meyer, Keith, Bose, Sandip K., Di Bisceglie, Adrian M., Ray, Ratna B., Diamond, Michael S., Atkinson, John P., Ray, Ranjit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700207/
https://ncbi.nlm.nih.gov/pubmed/23658447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00917-13
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