Hepatitis C Virus Infection Upregulates CD55 Expression on the Hepatocyte Surface and Promotes Association with Virus Particles

CD55 limits excessive complement activation on the host cell surface by accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes upregulated CD55 expression at the mRNA and pro...

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Detalhes bibliográficos
Main Authors: Mazumdar, Budhaditya, Kim, Hangeun, Meyer, Keith, Bose, Sandip K., Di Bisceglie, Adrian M., Ray, Ratna B., Diamond, Michael S., Atkinson, John P., Ray, Ranjit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700207/
https://ncbi.nlm.nih.gov/pubmed/23658447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00917-13
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