Hepatitis C Virus Infection Upregulates CD55 Expression on the Hepatocyte Surface and Promotes Association with Virus Particles

CD55 limits excessive complement activation on the host cell surface by accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes upregulated CD55 expression at the mRNA and pro...

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Hlavní autoři: Mazumdar, Budhaditya, Kim, Hangeun, Meyer, Keith, Bose, Sandip K., Di Bisceglie, Adrian M., Ray, Ratna B., Diamond, Michael S., Atkinson, John P., Ray, Ranjit
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700207/
https://ncbi.nlm.nih.gov/pubmed/23658447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00917-13
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