Hepatitis C Virus Suppresses C9 Complement Synthesis and Impairs Membrane Attack Complex Function

Hepatitis C virus (HCV) proteins inhibit complement component expression, which may attenuate immunity against infection. In this study, we examined whether HCV regulates the membrane attack complex (MAC) via complement component C9. MAC is composed of C5b to C9 (C5b-9) and mediates cell lysis of in...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Hangeun, Meyer, Keith, Di Bisceglie, Adrian M., Ray, Ranjit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648158/
https://ncbi.nlm.nih.gov/pubmed/23487461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00174-13
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