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Hepatitis C Virus Impairs Natural Killer Cell-Mediated Augmentation of Complement Synthesis
Natural killer (NK) cells and the complement system play critical roles in the first line of defense against pathogens. The synthesis of complement components C4 and C3 is transcriptionally downregulated by hepatitis C virus (HCV) core and NS5A proteins, and this negative regulation is apparent in c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3958077/ https://ncbi.nlm.nih.gov/pubmed/24352446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02988-13 |
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