p90 RSK2 Mediates Antianoikis Signals by both Transcription-Dependent and -Independent Mechanisms

How invasive and metastatic tumor cells evade anoikis induction remains unclear. We found that knockdown of RSK2 sensitizes diverse cancer cells to anoikis induction, which is mediated through phosphorylation targets including apoptosis signal-regulating kinase 1 (ASK1) and cyclic AMP (cAMP) respons...

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Detalhes bibliográficos
Main Authors: Jin, Lingtao, Li, Dan, Lee, Jong Seok, Elf, Shannon, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Wang, Dongsheng, Fu, Haian, Taunton, Jack, Boggon, Titus J., Tucker, Meghan, Gu, Ting-Lei, Chen, Zhuo G., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700113/
https://ncbi.nlm.nih.gov/pubmed/23608533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01677-12
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