ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1

Death receptor 5 (DR5) is a death domain-containing transmembrane receptor that triggers apoptosis upon binding to its ligand or when overexpressed. Its expression is induced by certain small molecule drugs, including celecoxib, through mechanisms that have not been fully elucidated. The current stu...

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Detalhes bibliográficos
Main Authors: Oh, You-Take, Liu, Xiangguo, Yue, Ping, Kang, Sumin, Chen, Jing, Taunton, Jack, Khuri, Fadlo R., Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009856/
https://ncbi.nlm.nih.gov/pubmed/21044953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153775
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