Complex Formation between S100B Protein and the p90 Ribosomal S6 Kinase (RSK) in Malignant Melanoma Is Calcium-dependent and Inhibits Extracellular Signal-regulated Kinase (ERK)-mediated Phosphorylation of RSK

S100B is a prognostic marker for malignant melanoma. Increasing S100B levels are predictive of advancing disease stage, increased recurrence, and low overall survival in malignant melanoma patients. Using S100B overexpression and shRNA(S100B) knockdown studies in melanoma cell lines, elevated S100B...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hartman, Kira G., Vitolo, Michele I., Pierce, Adam D., Fox, Jennifer M., Shapiro, Paul, Martin, Stuart S., Wilder, Paul T., Weber, David J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007476/
https://ncbi.nlm.nih.gov/pubmed/24627490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561613
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia