p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration

Cell migration is essential to embryonic development, wound healing, and cancer cell dissemination. Cells move via leading-edge protrusion, substrate adhesion, and retraction of the cell's rear. The molecular mechanisms by which extracellular cues signal to the actomyosin cytoskeleton to contro...

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Publicado en:J Biol Chem
Autores principales: Samson, Shiela C., Elliott, Andrew, Mueller, Brian D., Kim, Yung, Carney, Keith R., Bergman, Jared P., Blenis, John, Mendoza, Michelle C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635457/
https://ncbi.nlm.nih.gov/pubmed/31138649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007431
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