Engineered ascorbate peroxidase as a genetically-encoded reporter for electron microscopy

Electron microscopy (EM) is the standard method for imaging cellular structures with nanometer resolution, but existing genetic tags are inactive in most cellular compartments(1) or require light and are difficult to use(2). Here we report the development of a simple and robust EM genetic tag, calle...

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Bibliografiske detaljer
Main Authors: Martell, Jeffrey D., Deerinck, Thomas J., Sancak, Yasemin, Poulos, Thomas L., Mootha, Vamsi K., Sosinsky, Gina E., Ellisman, Mark H., Ting, Alice Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699407/
https://ncbi.nlm.nih.gov/pubmed/23086203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2375
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