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Engineering Ascorbate Peroxidase Activity into Cytochrome c Peroxidase

Cytochrome c peroxidase (CCP) and ascorbate peroxidase (APX) have very similar structures, and yet neither CCP nor APX exhibit each others activities with respect to reducing substrates. APX has a unique substrate binding site near the heme propionates where ascorbate H-bonds with a surface Arg and...

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Detalhes bibliográficos
Main Authors: Meharenna, Yergalem T., Oertel, Patricia, Bhaskar, B., Poulos, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770236/
https://ncbi.nlm.nih.gov/pubmed/18771292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8007565
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