Selective Inactivation of PTEN in Smooth Muscle Cells Synergizes With Hypoxia to Induce Severe Pulmonary Hypertension

BACKGROUND: Pulmonary vascular remodeling in pulmonary hypertension (PH) is characterized by increased vascular smooth muscle cell (SMC) and adventitial fibroblast proliferation, small vessel occlusion, and inflammatory cell accumulation. The underlying molecular mechanisms driving progression remai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Horita, Henrick, Furgeson, Seth B., Ostriker, Allison, Olszewski, Kyle A., Sullivan, Timothy, Villegas, Leah R., Levine, Michelle, Parr, Jane E., Cool, Carlyne D., Nemenoff, Raphael A., Weiser‐Evans, Mary C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698782/
https://ncbi.nlm.nih.gov/pubmed/23727701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000188
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados