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SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation
OBJECTIVE: PTEN inactivation selectively in smooth muscle cells (SMC) initiates multiple downstream events driving neointima formation, including SMC cytokine/chemokine production, in particular SDF-1α. We investigated the effects of SDF-1α on resident SMC and bone marrow-derived cells and in mediat...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111081/ https://ncbi.nlm.nih.gov/pubmed/21415388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.223701 |
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