SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation

OBJECTIVE: PTEN inactivation selectively in smooth muscle cells (SMC) initiates multiple downstream events driving neointima formation, including SMC cytokine/chemokine production, in particular SDF-1α. We investigated the effects of SDF-1α on resident SMC and bone marrow-derived cells and in mediat...

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Detalhes bibliográficos
Main Authors: Nemenoff, Raphael A., Horita, Henrick, Ostriker, Allison C., Furgeson, Seth B., Simpson, Peter A., VanPutten, Vicki, Crossno, Joseph, Offermanns, Stefan, Weiser-Evans, Mary C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111081/
https://ncbi.nlm.nih.gov/pubmed/21415388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.223701
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