T cell–derived inducible nitric oxide synthase switches off T(H)17 cell differentiation

RORγt is necessary for the generation of T(H)17 cells but the molecular mechanisms for the regulation of T(H)17 cells are still not fully understood. We show that activation of CD4(+) T cells results in the expression of inducible nitric oxide synthase (iNOS). iNOS-deficient mice displayed enhanced...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yang, Jianjun, Zhang, Ruihua, Lu, Geming, Shen, Yu, Peng, Liang, Zhu, Chen, Cui, Miao, Wang, Weidong, Arnaboldi, Paul, Tang, Meng, Gupta, Monica, Qi, Chen-Feng, Jayaraman, Padmini, Zhu, Hongfa, Jiang, Bo, Chen, Shu-hsia, He, John Cijiang, Ting, Adrian T., Zhou, Ming-Ming, Kuchroo, Vijay K., Morse, Herbert C., Ozato, Keiko, Sikora, Andrew G., Xiong, Huabao
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698516/
https://ncbi.nlm.nih.gov/pubmed/23797094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122494
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk