Cancer translocations in human cells induced by zinc finger and TALE nucleases

Chromosomal translocations are signatures of numerous cancers and lead to expression of fusion genes that act as oncogenes. The wealth of genomic aberrations found in cancer, however, makes it challenging to assign a specific phenotypic change to a specific aberration. In this study, we set out to u...

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Detalhes bibliográficos
Main Authors: Piganeau, Marion, Ghezraoui, Hind, De Cian, Anne, Guittat, Lionel, Tomishima, Mark, Perrouault, Loic, René, Oliver, Katibah, George E., Zhang, Lei, Holmes, Michael C., Doyon, Yannick, Concordet, Jean-Paul, Giovannangeli, Carine, Jasin, Maria, Brunet, Erika
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698511/
https://ncbi.nlm.nih.gov/pubmed/23568838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147314.112
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