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Human Mitochondrial RNA Polymerase: Evaluation of the Single-Nucleotide-Addition Cycle on Synthetic RNA/DNA Scaffolds

The human mitochondrial RNA polymerase (h-mtRNAP) serves as both the transcriptase for expression and the primase for replication of mitochondrial DNA. As such, the enzyme is of fundamental importance to cellular energy metabolism, and defects in its function may be related to human disease states....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smidansky, Eric D., Arnold, Jamie J., Reynolds, Shelley L., Cameron, Craig E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698222/
https://ncbi.nlm.nih.gov/pubmed/21548588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200350d
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