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The nucleotide addition cycle of the SARS-CoV-2 polymerase
Coronaviruses have evolved elaborate multisubunit machines to replicate and transcribe their genomes. Central to these machines are the RNA-dependent RNA polymerase subunit (nsp12) and its intimately associated cofactors (nsp7 and nsp8). We have used a high-throughput magnetic-tweezers approach to d...
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| Veröffentlicht in: | bioRxiv |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8010733/ https://ncbi.nlm.nih.gov/pubmed/33791706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.27.437309 |
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