Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

RNA viruses pose a threat to public health that is exacerbated by the dearth of antiviral therapeutics. The RNA-dependent RNA polymerase (RdRp) holds promise as a broad-spectrum, therapeutic target because of the conserved nature of the nucleotide-substrate-binding and catalytic sites. Conventional,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Dulin, David, Arnold, Jamie J., van Laar, Theo, Oh, Hyung-Suk, Lee, Cheri, Perkins, Angela L., Harki, Daniel A., Depken, Martin, Cameron, Craig E., Dekker, Nynke H.
Format: Artigo
Sprog:Inglês
Udgivet: The Authors. 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670035/
https://ncbi.nlm.nih.gov/pubmed/29069588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.005
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker