Recombinant Human Adenovirus-p53 Injection Induced Apoptosis in Hepatocellular Carcinoma Cell Lines Mediated by p53-Fbxw7 Pathway, Which Controls c-Myc and Cyclin E

F-box and WD repeat domain-containing 7 (Fbxw7/hAgo/hCdc4/Fbw7) is a p53-dependent tumor suppressor and leads to ubiquitination-mediated suppression of several oncoproteins including c-Myc, cyclin E, Notch, c-Jun and others. Our previous study has indicated that low expression of Fbxw7 was negativel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tu, Kangsheng, Zheng, Xin, Zhou, Zhenyu, Li, Chao, Zhang, Jing, Gao, Jie, Yao, Yingmin, Liu, Qingguang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698167/
https://ncbi.nlm.nih.gov/pubmed/23840897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068574
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados