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p53-expressing conditionally replicative adenovirus CNHK500-p53 against hepatocellular carcinoma in vitro

AIM: To develop a conditionally replicative gene-viral vector system called CNHK500-p53, which contains dual promoters within the E1 region, and combines the advantages of oncolytic virus and gene therapies for hepatocellular carcinoma (HCC). METHODS: CNHK500-p53 was constructed by using human telom...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhao, Hong-Chuan, Zhang, Qi, Yang, Yang, Lu, Min-Qiang, Li, Hua, Xu, Chi, Chen, Gui-Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Co., Limited 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066000/
https://ncbi.nlm.nih.gov/pubmed/17278190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i5.683
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