Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) has a dismal 5-year-survival rate of 10%, so novel strategies are warranted. IL-24 mediates anti-tumor activity reducing STAT3 expression, which suggests that interferon (IFN) alpha may augment tumor cell lysis and reduce angiogenesis. We investigated the a...

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Detalhes bibliográficos
Main Authors: Wang, Cong-Jun, Xiao, Chao-Wen, You, Tian-Geng, Zheng, Ya-Xin, Gao, Wei, Zhou, Zhu-Qing, Chen, Jun, Xue, Xin-Bo, Fan, Jia, Zhang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697897/
https://ncbi.nlm.nih.gov/pubmed/22569271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-31
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