Antitumor activity of an hTERT promoter-regulated tumor-selective oncolytic adenovirus in human hepatocellular carcinoma

AIM: To construct a tumor-selective replication-competent adenovirus (RCAd), SG300, using a modified promoter of human telomerase reverse transcriptase (hTERT). METHODS: The antitumor efficacy of SG300 in hepatocellular carcinoma was assessed in vitro and in vivo. In vitro cell viability by MTT assa...

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Dettagli Bibliografici
Autori principali: Su, Chang-Qing, Wang, Xing-Hua, Chen, Jie, Liu, Yong-Jing, Wang, Wei-Guo, Li, Lin-Fang, Wu, Meng-Chao, Qian, Qi-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Co., Limited 2006
Soggetti:
Liver Cancer
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088042/
https://ncbi.nlm.nih.gov/pubmed/17171789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i47.7613
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