Enhancement of tumor cell death by combining cisplatin with an oncolytic adenovirus carrying MDA-7/IL-24

AIM: The aim of this study was to creatively implement a novel chemo-gene-virotherapeutic strategy and further strengthen the antitumor effect in cancer cells by the combined use of ZD55-IL-24 and cisplatin. METHODS: ZD55-IL-24 is an oncolytic adenovirus that harbors interleukin 24 (IL-24), which ha...

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Autors principals: Wu, Yu-mei, Zhang, Kang-jian, Yue, Xue-tian, Wang, Yi-qiang, Yang, Yi, Li, Gong-chu, Li, Na, Wang, Yi-gang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002269/
https://ncbi.nlm.nih.gov/pubmed/19270721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.16
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