Use of Antistaphylococcal β-Lactams to Increase Daptomycin Activity in Eradicating Persistent Bacteremia Due to Methicillin-Resistant Staphylococcus aureus: Role of Enhanced Daptomycin Binding

We used daptomycin plus antistaphylococcal β-lactams (ASBL) to clear refractory MRSA bacteremia. In vitro studies showed enhanced daptomycin bactericidal activity, increased membrane daptomycin binding, and decrease in positive surface charge induced by ASBLs against daptomycin nonsusceptible MRSA....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dhand, Abhay, Bayer, Arnold S., Pogliano, Joseph, Yang, Soo-Jin, Bolaris, Michael, Nizet, Victor, Wang, Guiquing, Sakoulas, George
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2011
Aiheet:
Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697476/
https://ncbi.nlm.nih.gov/pubmed/21690622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cir340
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