β-Lactam-Induced Cell Envelope Adaptations, Not Solely Enhanced Daptomycin Binding, Underlie Daptomycin-β-Lactam Synergy in Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a serious clinical threat due to innate virulence properties, high infection rates, and the ability to develop resistance to multiple antibiotics, including the lipopeptide daptomycin (DAP). The acquisition of DAP resistance (DAP-R) in MRSA has b...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Lew, Cassandra, Mishra, Nagendra N., Bayer, Arnold S., Rose, Warren E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284448/
https://ncbi.nlm.nih.gov/pubmed/34097478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00356-21
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