Cell Membrane Adaptations Mediate β-Lactam-Induced Resensitization of Daptomycin-Resistant (DAP-R) Staphylococcus aureus In Vitro

The reversal of daptomycin resistance in MRSA to a daptomycin-susceptible phenotype following prolonged passage in selected β-lactams occurs coincident with the accumulation of multiple point mutations in the mprF gene. MprF regulates surface charge by modulating the content and translocation of the...

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Détails bibliographiques
Publié dans:Microorganisms
Auteurs principaux: Mishra, Nagendra N., Bayer, Arnold S., Baines, Sarah L., Hayes, Ashleigh S., Howden, Benjamin P., Lapitan, Christian K., Lew, Cassandra, Rose, Warren E.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150363/
https://ncbi.nlm.nih.gov/pubmed/34064631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9051028
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