ACH-806, an NS4A Antagonist, Inhibits Hepatitis C Virus Replication by Altering the Composition of Viral Replication Complexes

Treatment of hepatitis C patients with direct-acting antiviral drugs involves the combination of multiple small-molecule inhibitors of distinctive mechanisms of action. ACH-806 (or GS-9132) is a novel, small-molecule inhibitor specific for hepatitis C virus (HCV). It inhibits viral RNA replication i...

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Autori principali: Yang, Wengang, Sun, Yongnian, Hou, Xiaohong, Zhao, Yongsen, Fabrycki, Joanne, Chen, Dawei, Wang, Xiangzhu, Agarwal, Atul, Phadke, Avinash, Deshpande, Milind, Huang, Mingjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697357/
https://ncbi.nlm.nih.gov/pubmed/23629709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02630-12
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