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Synthesis and evaluation of 7-substituted 4-aminoquinoline analogs for antimalarial activity

We previously reported that substituted 4-aminoquinolines with a phenylether substituent at the 7-position of the quinoline ring and the capability of intramolecular hydrogen bonding between the protonated amine on the side chain and a hydrogen bond acceptor on the amine’s alkyl substituents exhibit...

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Detalhes bibliográficos
Main Authors: Hwang, Jong Yeon, Kawasuji, Takashi, Lowes, David J., Clark, Julie A., Connelly, Michele C., Zhu, Fangyi, Guiguemde, W. Armand, Sigal, Martina S., Wilson, Emily B., DeRisi, Joseph L., Guy, R. Kiplin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697074/
https://ncbi.nlm.nih.gov/pubmed/21910466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200636z
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