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Re-Directing CD4(+) T Cell Responses with the Flanking Residues of MHC Class II-Bound Peptides: The Core is Not Enough

Recombinant αβ T cell receptors, expressed on T cell membranes, recognize short peptides presented at the cell surface in complex with MHC molecules. There are two main subsets of αβ T cells: CD8(+) T cells that recognize mainly cytosol-derived peptides in the context of MHC class I (pMHC-I), and CD...

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Bibliographic Details
Main Authors: Holland, Christopher J., Cole, David K., Godkin, Andrew
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696884/
https://ncbi.nlm.nih.gov/pubmed/23847615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00172
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