Single-Molecule Motions of MHC Class II Rely on Bound Peptides

The major histocompatibility complex (MHC) class II protein can bind peptides of different lengths in the region outside the peptide-binding groove. Peptide-flanking residues (PFRs) contribute to the binding affinity of the peptide for MHC and change the immunogenicity of the peptide/MHC complex wit...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Kozono, Haruo, Matsushita, Yufuku, Ogawa, Naoki, Kozono, Yuko, Miyabe, Toshihiro, Sekiguchi, Hiroshi, Ichiyanagi, Kouhei, Okimoto, Noriaki, Taiji, Makoto, Kanagawa, Osami, Sasaki, Yuji C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302206/
https://ncbi.nlm.nih.gov/pubmed/25606683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.004
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