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BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells
Amyloids are often associated with pathologic processes such as in Alzheimer’s disease (AD), but can also underlie physiological processes such as pigmentation. Formation of pathological and functional amyloidogenic substrates can require precursor processing by proteases, as exemplified by the gene...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696817/ https://ncbi.nlm.nih.gov/pubmed/23754390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220748110 |
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